Improved Cytokines IL-2 Pro

Compared with wild-type IL-2, IL-2 Pro can slowly activate regulatory T cells (Treg), reduce the negative regulation of the immune  system, and give full play to theimmunomodulatory function of T cells to a greater extent. This product has high solubility, strong purity  and specificity, and is more convenient to use in relevant drug processes and R & D.

EXPERIMENTAL DATA

Activity comparison between IL-2Pro and wild-typeIL-2

• the results show that compared with wild-type IL-2, IL-2 Pro can slowly activate regulatory T cells (Treg).

Activity comparison between IL-2Pro and IL-2(CTLL-2cells)

• The experiment on the activity of mouse T lymphocytes (CTLL-2)  cells shows that the activity of IL-2 Pro is similar to that of IL-2.

Purity analysis of IL-2Pro by SDS-PAGE and SEC-HPLC 

• SDS PAGE showed that the molecular weight of the protein was approximately 17 kDa and no impurity proteins were observed SEC HPLC showed high purity and no aggregates were produced.

  
  

Solubility determination

• Under the conditionof pH7 4 the con centration of IL 2Pro can reach 12 5mg ml which is 25 times that of the wild type.

  
  

PRODUCT FEATURES

• High activity and bias

• High purity and high solubility

• Strong batch-to-batch stability